(CNN Health) – Researchers at Duke University have begun testing a Pfizer vaccine for the Coronavirus in children under the age of 12, the company told CNN Thursday, at least two children have already received the first dose.
The company begins its trials first in the 5-11 year olds to determine the appropriate dose, starting with 10 micrograms of the vaccine.
If this dose was tolerated, the study would escalate the dose to 20 micrograms, then 30 micrograms. There is also a 3 mcg option. An adult dose of Pfizer vaccine contains 30 micrograms.
And just like adult dosing, children will also be on a two-dose schedule, with a 21-day break.
If 10 micrograms were tolerated in the 5-11 year old group, the trial would also follow the same process for the 2 to 5 year olds, and then for younger children 6 months to 2 years old.
The trials will include 144 children under the age of twelve. Two-thirds of the children will get a vaccine and a third will get a placebo. At a six-month follow-up, all participants would be free of blindness and those taking placebo would be eligible for the vaccine.